The biology, pathology and therapeutic use of prostaglandins in the eye

@article{Toris2011TheBP,
  title={The biology, pathology and therapeutic use of prostaglandins in the eye},
  author={Carol B. Toris and Vikas Gulati},
  journal={Clinical Lipidology},
  year={2011},
  volume={6},
  pages={577 - 591}
}
Abstract Prostaglandins (PGs) are ubiquitous compounds found throughout the body, including the eye. They are involved in a variety of ocular functions, two of which are intraocular pressure (IOP) regulation and mediation of inflammation. Currently, PG analogs are the mainstay of topical IOP lowering therapy for glaucoma. The IOP effects of PGs are mediated by their actions on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases, thereby facilitating the outflow of… 
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