The biological significance of tobacco-specific N-nitrosamines: smoking and adenocarcinoma of the lung.

@article{Hoffmann1996TheBS,
  title={The biological significance of tobacco-specific N-nitrosamines: smoking and adenocarcinoma of the lung.},
  author={Dietrich Hoffmann and Abraham Rivenson and Stephen S Hecht},
  journal={Critical reviews in toxicology},
  year={1996},
  volume={26 2},
  pages={199-211}
}
In the U.S., there has been a steeper rise of the incidence of lung adenocarcinoma than of squamous cell carcinoma of the lung among cigarette smokers. Since 1950, the percentage of all cigarettes sold that had filter tips increased from 0.56 to 92% in 1980 and to 97% in 1990. The tobacco of the filter cigarettes is richer in nitrate than that of the nonfilter cigarettes manufactured in past decades. Because the smoker of cigarettes with lower nicotine yield tends to smoke more intensely and to… CONTINUE READING
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