The biological significance of plasmalogens in defense against oxidative damage

@article{Brosche1998TheBS,
  title={The biological significance of plasmalogens in defense against oxidative damage},
  author={Thorolf Brosche and Dieter Platt},
  journal={Experimental Gerontology},
  year={1998},
  volume={33},
  pages={363-369}
}
The phospholipid class of plasmalogens is ubiquitously found in considerable amounts as a constituent of mammalian cell membranes and of plasma lipoproteins. Plasmalogens are more susceptible to oxidative reactions compared to their fatty acid ester analogues, due to the reactivity of their enolether function. Studies on plasmalogen-deficient cell lines lead to the proposal that these ether lipids serve as endogenous antioxidants. No clear conclusions regarding the antioxidative effects of… CONTINUE READING
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