The biological role of dectin-1 in immune response.

  title={The biological role of dectin-1 in immune response.},
  author={Lina Sun and Yong Zhao},
  journal={International reviews of immunology},
  volume={26 5-6},
The identification of antigen-recognizing receptors in the innate immune system significantly helped us to understand the initiation and regulation of the innate immune response. Dectin-1 was recently identified as the most important receptor for beta-glucan. Recognition of beta-glucan by dectin-1 triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi, which especially benefits immunocompromised patients against… CONTINUE READING
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