The biological impact of mass-spectrometry-based proteomics

@article{Cravatt2007TheBI,
  title={The biological impact of mass-spectrometry-based proteomics},
  author={Benjamin F Cravatt and Gabriel M. Simon and John R. Yates},
  journal={Nature},
  year={2007},
  volume={450},
  pages={991-1000}
}
In the past decade, there have been remarkable advances in proteomic technologies. Mass spectrometry has emerged as the preferred method for in-depth characterization of the protein components of biological systems. Using mass spectrometry, key insights into the composition, regulation and function of molecular complexes and pathways have been gained. From these studies, it is clear that mass-spectrometry-based proteomics is now a powerful 'hypothesis-generating engine' that, when combined with… CONTINUE READING
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