The biological effect of a nonprotein component removed from neocarzinostatin (NCS).

@article{Ohtsuki1980TheBE,
  title={The biological effect of a nonprotein component removed from neocarzinostatin (NCS).},
  author={Kenzo Ohtsuki and Nobuhiro Ishida},
  journal={The Journal of antibiotics},
  year={1980},
  volume={33 7},
  pages={744-50}
}
The biological effects of both nonprotein component (NPC) and PC (protein component) from NCS have been studied in vivo and in vitro. NPC was found to not only inhibit DNA synthesis in growing cells but also induce DNA degradation in vivo and in vitro. However, neither these two biological activities of PC were detected even at a 100-times higher… CONTINUE READING