The biological cost of antibiotic resistance.

@article{Andersson1999TheBC,
  title={The biological cost of antibiotic resistance.},
  author={Dan I Andersson and Bruce R. Levin},
  journal={Current opinion in microbiology},
  year={1999},
  volume={2 5},
  pages={489-93}
}
The frequency and rates of ascent and dissemination of antibiotic resistance in bacterial populations are anticipated to be directly related to the volume of antibiotic use and inversely related to the cost that resistance imposes on the fitness of bacteria. The data available from recent laboratory studies suggest that most, but not all, resistance-determining mutations and accessory elements engender some fitness cost, but those costs are likely to be ameliorated by subsequent evolution. 
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
292 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 292 extracted citations

Similar Papers

Loading similar papers…