The biological characteristics of CD34+ CD2+ adult acute promyelocytic leukemia and the CD34 CD2 hypergranular (M3) and microgranular (M3v) phenotypes.

@article{Albano2006TheBC,
  title={The biological characteristics of CD34+ CD2+ adult acute promyelocytic leukemia and the CD34 CD2 hypergranular (M3) and microgranular (M3v) phenotypes.},
  author={Francesco Albano and Anna Mestice and Alessandra Pannunzio and Francesco Lanza and Bruno Martino and Domenico Pastore and Felicetto Ferrara and Paola Carluccio and Francesco Nobile and Gianluigi Castoldi and Vincenzo Liso and Giorgina Specchia},
  journal={Haematologica},
  year={2006},
  volume={91 3},
  pages={311-6}
}
BACKGROUND AND OBJECTIVES Acute promyelocytic leukemia (APL) is characterized by leukemic cells blocked at the promyelocytic stage of granulocytic differentiation. To date, it is still not clear whether CD34 expression identifies a subset of APL patients with peculiar characteristics. We, therefore, conducted a detailed analysis of CD34 expression at diagnosis in 136 adults with de novo APL. DESIGN AND METHODS We investigated 136 newly diagnosed APL patients from four Italian Institutions… CONTINUE READING

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