The biological activity of pantolactone and pantoic acid.

  title={The biological activity of pantolactone and pantoic acid.},
  author={P. Stansly and M. Schlosser},
  journal={The Journal of biological chemistry},
  • P. Stansly, M. Schlosser
  • Published 1945
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • As far as we are aware, no distinction has been made between the biological activity of pantolactone (CL, y-dihydroxy-p, fl-dimethylbutyrolactone) and pantoic acid or its ion.1 In connection with studies on the antagonistic action of pantoyltaurine on salicylate inhibition of Escherichia coli 2 we have observed that pantoic acid, or, more properly, the pantoate ion, is more active than pantolactone. In low concentrations, salicylic acid is thought to inhibit growth of bacteria which synthesize… CONTINUE READING
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    I’., and Cheldelin, 5
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    • 1945