The biological activity of auranofin: implications for novel treatment of diseases

@article{Madeira2012TheBA,
  title={The biological activity of auranofin: implications for novel treatment of diseases},
  author={Jocelyn M. Madeira and David S. Gibson and Walter F. Kean and Andis Klegeris},
  journal={Inflammopharmacology},
  year={2012},
  volume={20},
  pages={297-306}
}
More than 30 years ago, auranofin was developed for the treatment of rheumatoid arthritis as a substitution for the injectable gold compounds aurothiomalate and aurothioglucose. Both the ease of oral administration over intramuscular injections and more potent anti-inflammatory effects in vitro made auranofin seem like an excellent substitute for the… CONTINUE READING