The bioenergetic and gas exchange basis of exercise testing.

@article{Whipp1994TheBA,
  title={The bioenergetic and gas exchange basis of exercise testing.},
  author={Brian Whipp},
  journal={Clinics in chest medicine},
  year={1994},
  volume={15 2},
  pages={173-92}
}
Exercise intolerance results when a subject is unable to sustain a required work rate sufficiently long for the successful completion of the task. The ability to sustain muscular exercise depends in large part on the ability to transport oxygen to its site of utilization as the terminal oxidant of the mitochondrial electron transport chain. This requires a… CONTINUE READING