The biochemistry and pharmacology of excitatory sulphur-containing amino acids.

@article{Griffiths1993TheBA,
  title={The biochemistry and pharmacology of excitatory sulphur-containing amino acids.},
  author={R. Griffiths},
  journal={Biochemical Society transactions},
  year={1993},
  volume={21 1},
  pages={
          66-72
        }
}
  • R. Griffiths
  • Published 1993
  • Chemistry, Medicine
  • Biochemical Society transactions
  • 1,-Glutamate is now well established as the predominant transmitter at fast-acting excitatory synapses in the mammalian central nervous system. Other amino acids such as L-aspartate and several acidic sulphur-containing amino acids (SAAs) which exhibit potent depolarizing actions similar to that of Lglutamate [I-31 are known to exist in the brain and/or are present in the brain under pathological conditions. The putative SAA transmitters (see Figure 1) comprise the L-aspartate analogues… CONTINUE READING
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