The biochemical pathology of aspirin-induced gastric damage

@article{Rainsford1975TheBP,
  title={The biochemical pathology of aspirin-induced gastric damage},
  author={Kim Drummond Rainsford},
  journal={Agents and Actions},
  year={1975},
  volume={5},
  pages={326-344}
}
The development of gastric damage is probably the most serious side-effect associated with aspirin ingestion [1]. Clinical studies have implicated aspirin as a major causative agent in the development of gastric and duodenal ulcers [2-4]. Many patients with the clinical syndrome of 'analgesic abuse' have gastrointestinal pathology as well as severe renal… CONTINUE READING