The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity.

@article{Buchsbaum1976TheBH,
  title={The biochemical high-risk paradigm: behavioral and familial correlates of low platelet monoamine oxidase activity.},
  author={Monte S. Buchsbaum and Robert D Coursey and Dennis L. Murphy},
  journal={Science},
  year={1976},
  volume={194 4262},
  pages={339-41}
}
A population of individuals potentially at risk for psychiatric disorders was identified by screening 375 college student volunteers for low platelet monoamine oxidase (MAO) activity levels. The lower and upper 10 per cent in MAO activity were interviewed and family history data were obtained. Low-MAO probands reported more frequent psychiatric or psychological counseling and problems with the law. Families of low MAO probands had an eightfold increase in the incidence of suicide or suicide… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

Similar Papers

Loading similar papers…