The biochemical basis of metabolism in cancer cachexia.

  title={The biochemical basis of metabolism in cancer cachexia.},
  author={Amanda J Tijerina},
  journal={Dimensions of critical care nursing : DCCN},
  volume={23 6},
Cancer cachexia is a syndrome of progressive body wasting characterized by loss of adipose tissue and skeletal muscle mass. It is the most common side effect of malignancy occurring in approximately one-half of untreated cancer patients. The pathophysiology of cancer cachexia is not fully understood; however, studies have shown that cytokines are important in the alteration of carbohydrate, lipid, and protein metabolism. This leads to a shorter survival time and a decreased response to therapy… CONTINUE READING
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