The biochemical basis of hereditary fructose intolerance

@article{Bouteldja2010TheBB,
  title={The biochemical basis of hereditary fructose intolerance},
  author={Nadia Bouteldja and D. Timson},
  journal={Journal of Inherited Metabolic Disease},
  year={2010},
  volume={33},
  pages={105-112}
}
Hereditary fructose intolerance is a rare, but potentially lethal, inherited disorder of fructose metabolism, caused by mutation of the aldolase B gene. Treatment currently relies solely on dietary restriction of problematic sugars. Biochemical study of defective aldolase B enzymes is key to revealing the molecular basis of the disease and providing a stronger basis for improved treatment and diagnosis. Such studies have revealed changes in enzyme activity, stability and oligomerisation… Expand
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