The binding of hepatitis B virus X protein to glioma-associated oncogene homologue 1 and its biological characterization in vitro.

@article{Jo2011TheBO,
  title={The binding of hepatitis B virus X protein to glioma-associated oncogene homologue 1 and its biological characterization in vitro.},
  author={Bo Bae Jo and Mi Suk Jeong and So Young Park and Jaehun Cheong and Se Bok Jang},
  journal={Applied biochemistry and biotechnology},
  year={2011},
  volume={165 1},
  pages={109-22}
}
Hepatitis B virus (HBV) X protein (HBx) is a 17-kDa transcriptional coactivator that plays a significant role in the regulation of genes involved in inflammation and cell survival. It has been known to be involved in the development of liver cancer and alteration of the cellular HBx level may influence the pathogenesis of HBV-induced liver diseases. The transcription factor GLI1, a member of the glioma-associated oncogene homologue (GLI) subfamily of Krüppel-like zinc finger proteins is… CONTINUE READING