The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).

@article{Liu1999TheBI,
  title={The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).},
  author={Qiang Liu and Changwen Jin and Xiubei Liao and Zhiyuan Shen and David J. Chen and Yuan Fang Chen},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 24},
  pages={16979-87}
}
Human UBC9 is a member of the E2 (ubiquitin conjugation enzyme) family of proteins. Instead of conjugating to ubiquitin, it conjugates with a ubiquitin homologue UBL1 (also known as SUMO-1, GMP1, SMTP3, PIC1, and sentrin). UBC9 has been shown to be involved in cell cycle regulation, DNA repair, and p53-dependent processes. The binding interfaces of the UBC9 and UBL1 complex have been determined by chemical shift perturbation using nuclear magnetic resonance spectroscopy. The binding site of… CONTINUE READING

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The Binding Interfaces between UBC9 and UBL1

  • M. L. Sullivan, R. D. Vierstra
  • J. Biol. Chem. 266,
  • 1991
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