The bias introduced by population stratification in IBD based linkage analysis.

Abstract

The lack of replication of model-free linkage analyses performed on complex diseases raises questions about the robustness of these methods to various biases. The confounding effect of population stratification on a genetic association study has long been recognized in the genetic epidemiology community. Because the estimation of the number of alleles… (More)

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Cite this paper

@article{Wang2005TheBI, title={The bias introduced by population stratification in IBD based linkage analysis.}, author={Tao Wang and Robert C. Elston}, journal={Human heredity}, year={2005}, volume={60 3}, pages={134-42} }