The beta-globin gene haplotypes associated with Hb D-Los Angeles [beta121(GH4)Glu --> Gln] in Western Iran.

@article{Rahimi2006TheBG,
  title={The beta-globin gene haplotypes associated with Hb D-Los Angeles [beta121(GH4)Glu --> Gln] in Western Iran.},
  author={Zohreh Rahimi and Reza Akramipour and Ronald L. Nagel and Ali Shahriari Ahmadi and Ahmad Merat and Fariborz Bahrehmand},
  journal={Hemoglobin},
  year={2006},
  volume={30 1},
  pages={39-44}
}
Hb D-Los Angeles is characterized by the substitution of glutamine for glutamic acid at position 121 of the beta-globin chain. The present investigation is the first study on the beta-globin gene haplotypes associated with beta-D-Los Angeles in Western Iran. Thirty two individuals from 11 unrelated families from Western Iran were studied. The Hb D-Los Angeles status of all cases was confirmed using polymerase chain reaction (PCR) followed by digestion with EcoRl. The haplotype of the beta… CONTINUE READING