The beneficial effect of repaglinide on in vitro maturation and development ability of immature mouse oocytes

Abstract

Repaglinide is a hypoglycemic drug, causing depolarization of the cell membrane, opening the voltage-gated calcium channels, and then increasing intracellular calcium in the pancreatic B cells by inhibition of the K-ATP-sensitive channels. Oocyte in vitro maturation (IVM) is influenced by different factors such as calcium signaling. In this study, we… (More)
DOI: 10.1007/s11626-017-0152-3

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