The behavioral effects of CCK8 injected into the medial nucleus accumbens are dependent on the motivational state of the rat.

@article{Daug1989TheBE,
  title={The behavioral effects of CCK8 injected into the medial nucleus accumbens are dependent on the motivational state of the rat.},
  author={Val{\'e}rie Daug{\'e} and Anna Dor and Jean F{\'e}ger and B. Roques},
  journal={European journal of pharmacology},
  year={1989},
  volume={163 1},
  pages={25-32}
}
The effects of CCK8 injected into the rat median nucleus accumbens on exploration and locomotion were measured in the four hole box and open-field tests. CCK8 (1 fmol to 100 pmol) induced hypoexploration in the four hole box (duration, frequency), with the pattern of the responses remaining unchanged compared to those of the control group. These effects were reversed by injection of the CCK antagonist proglumide (20 micrograms) into the nucleus accumbens. In the open-field test, CCK8 (100 pmol… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…