The before/after study design in transfusion medicine: methodologic considerations.

@article{Fergusson2002TheBS,
  title={The before/after study design in transfusion medicine: methodologic considerations.},
  author={Dean Fergusson and Paul C. H{\'e}bert and Stan Shapiro},
  journal={Transfusion medicine reviews},
  year={2002},
  volume={16 4},
  pages={296-303}
}
To ascertain the effectiveness of an intervention, a randomized controlled trial (RCT) is considered the gold standard. An obstacle to conducting an RCT only rarely discussed is the universal implementation of an intervention. Universal implementation clearly precludes the feasibility of conducting an RCT. Thus, the most attractive alternative study design in such instances becomes the before/after study. This article describes important methodologic considerations in undertaking a before/after… CONTINUE READING