The bee venom test: a new tonic-pain test

@article{Lariviere1996TheBV,
  title={The bee venom test: a new tonic-pain test},
  author={William R. Lariviere and Ronald Melzack},
  journal={PAIN{\textregistered}},
  year={1996},
  volume={66},
  pages={271-277}
}
&NA; The present study describes a new test of tonic pain to be used as an animal model of persistent pain. First, pain responses and edema produced by subcutaneous injection of increasing doses of honey bee venom into the hind paw of the rat were quantified. Second, the effect of morphine and aspirin on the pain responses was investigated. Finally, the response to concurrent injections of bee venom and formalin was examined. Subcutaneous injection of bee venom produced local inflammation… Expand
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  • Sheng li xue bao : [Acta physiologica Sinica]
  • 2008
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