The basophil activation test in the diagnosis of allergy: technical issues and critical factors.

@article{Sturm2009TheBA,
  title={The basophil activation test in the diagnosis of allergy: technical issues and critical factors.},
  author={Gunter Johannes Sturm and Bettina Kranzelbinder and Eva M Sturm and Akos Heinemann and Andrea Groselj-Strele and Werner Aberer},
  journal={Allergy},
  year={2009},
  volume={64 9},
  pages={1319-26}
}
BACKGROUND The basophil activation test (BAT) is a widely validated and reliable tool especially for the diagnosis of hymenoptera venom allergy. Nevertheless, several pitfalls have to be considered and outcomes may differ because of diverse in-house protocols and commercially available kits. We aimed to identify the factors that may influence results of the CD63-based BAT. METHODS Basophil responses to monoclonal anti-IgE (clone E124.2.8) and bee and wasp venom were determined by BAT based on… CONTINUE READING

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