The basolateral organic cation transport system of rabbit kidney proximal tubules. Influence of anorganic anions.

@article{Hohage1996TheBO,
  title={The basolateral organic cation transport system of rabbit kidney proximal tubules. Influence of anorganic anions.},
  author={Helge Hohage and I U Querl and Dina Moerth and J. A. A. Greven},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1996},
  volume={279 3},
  pages={1086-91}
}
The influence of different extracellular chloride concentrations of chloride channel blockers and of inorganic anions on renal basolateral organic cation transport was examined on isolated nonperfused S2 segments of superficial proximal tubules of rabbit kidney. Tritium-labeled tetraethylammonium (TEA) with a high specific activity of 13.5 Ci/mmol was used as a model substrate of the organic cation transport system. With the experimental conditions chosen, the TEA accumulation in the cells… CONTINUE READING