The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors.

@article{Wang2006TheBH,
  title={The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors.},
  author={Duncheng Wang and Carol L. Claus and Giovanna Vaccarelli and Marsela Braunstein and Thomas M Schmitt and Juan Carlos Z{\'u}{\~n}iga-Pfl{\"u}cker and Ellen V Rothenberg and Michele K Anderson},
  journal={Journal of immunology},
  year={2006},
  volume={177 1},
  pages={109-19}
}
The basic helix-loop-helix (bHLH) transcription factors HEB and E2A are critical mediators of gene regulation during lymphocyte development. We have cloned a new transcription factor, called HEBAlt, from a pro-T cell cDNA library. HEBAlt is generated by alternative transcriptional initiation and splicing from the HEB gene locus, which also encodes the previously characterized E box protein HEBCan. HEBAlt contains a unique N-terminal coding exon (the Alt domain) that replaces the first… CONTINUE READING

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