The base excision repair pathway.

@article{Seeberg1995TheBE,
  title={The base excision repair pathway.},
  author={Erling Seeberg and Lars Eide and Magnar Bj\or{\aa}s},
  journal={Trends in biochemical sciences},
  year={1995},
  volume={20 10},
  pages={391-7}
}
The base excision repair pathway has evolved to protect cells from the deleterious effects of endogenous DNA damage induced by hydrolysis, reactive oxygen species and other intracellular metabolites that modify DNA base structure. However, base excision repair is also important to resist lesions produced by ionizing radiation and strong alkylating agents… CONTINUE READING