The basal proton conductance of mitochondria depends on adenine nucleotide translocase content.

@article{Brand2005TheBP,
  title={The basal proton conductance of mitochondria depends on adenine nucleotide translocase content.},
  author={Martin D. Brand and Julian L. Pakay and Augustine Ocloo and Jason E. Kokoszka and Douglas C. Wallace and Paul S Brookes and Emma J Cornwall},
  journal={The Biochemical journal},
  year={2005},
  volume={392 Pt 2},
  pages={353-62}
}
The basal proton conductance of mitochondria causes mild uncoupling and may be an important contributor to metabolic rate. The molecular nature of the proton-conductance pathway is unknown. We show that the proton conductance of muscle mitochondria from mice in which isoform 1 of the adenine nucleotide translocase has been ablated is half that of wild-type controls. Overexpression of the adenine nucleotide translocase encoded by the stress-sensitive B gene in Drosophila mitochondria increases… CONTINUE READING
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The role of the adenine nucleotide translocase in mitochondrial proton leak

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No evidence for a basal, retinoic, or superoxideinduced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria

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