The basal kinetic parameters of glycogen synthase in human myotube cultures are not affected by chronic high insulin exposure.

Abstract

There is no consensus regarding the results from in vivo and in vitro studies on the impact of chronic high insulin and/or high glucose exposure on acute insulin stimulation of glycogen synthase (GS) kinetic parameters in human skeletal muscle. The aim of this study was to evaluate the kinetic parameters of glycogen synthase activity in human myotube… (More)

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