The balancing effect between MAPK and NFκB pathways for the transcriptional regulation of Toll-like receptors
@inproceedings{Hong2016TheBE,
title={The balancing effect between MAPK and NFκB pathways for the transcriptional regulation of Toll-like receptors},
author={Xinyang Hong},
year={2016}
}Toll-like receptors (TLR) are a family of pattern recognition receptors crucial for pathogen pattern recognition. Upon activation, TLRs induce innate immune responses such as cytokine production. However irregular TLR activities can provide fatal, hence fine tuning of the TLR induced responses are necessary. The TLR mediated immune responses are controlled by the positive/negative regulation of TLR signalling pathways, relocation of TLR proteins and modulation of TLR transcription. Systematic… CONTINUE READING
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