• Corpus ID: 90392289

The balancing effect between MAPK and NFκB pathways for the transcriptional regulation of Toll-like receptors

  title={The balancing effect between MAPK and NF$\kappa$B pathways for the transcriptional regulation of Toll-like receptors},
  author={Xinyang Hong},
  • X. Hong
  • Published 2016
  • Biology, Environmental Science
Toll-like receptors (TLR) are a family of pattern recognition receptors crucial for pathogen pattern recognition. Upon activation, TLRs induce innate immune responses such as cytokine production. However irregular TLR activities can provide fatal, hence fine tuning of the TLR induced responses are necessary. The TLR mediated immune responses are controlled by the positive/negative regulation of TLR signalling pathways, relocation of TLR proteins and modulation of TLR transcription. Systematic… 


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