The bacteriophage lambdaQ anti-terminator protein regulates late gene expression as a stable component of the transcription elongation complex.

@article{Deighan2007TheBL,
  title={The bacteriophage lambdaQ anti-terminator protein regulates late gene expression as a stable component of the transcription elongation complex.},
  author={Padraig Deighan and Ann Hochschild},
  journal={Molecular microbiology},
  year={2007},
  volume={63 3},
  pages={
          911-20
        }
}
The Q protein of bacteriophage lambda (lambdaQ) is a transcription anti-terminator required for the expression of the phage's late genes under the control of promoter P(R'). To effect terminator read-through, lambdaQ must gain access to RNA polymerase (RNAP) via a promoter-restricted pathway. In particular, lambdaQ modifies RNAP by binding a specific DNA site embedded in P(R') and interacting with RNAP in the context of a specific paused early elongation complex. The resultant lambdaQ-modified… CONTINUE READING
Highly Cited
This paper has 24 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Precisely modulated pathogenicity island interference with late phage gene transcription.

Proceedings of the National Academy of Sciences of the United States of America • 2014
View 1 Excerpt