The bacterial envelope as a target for novel anti-MRSA antibiotics.

@article{Bambeke2008TheBE,
  title={The bacterial envelope as a target for novel anti-MRSA antibiotics.},
  author={Françoise Van Bambeke and Marie-Paule Mingeot-Leclercq and Marc Jean Struelens and Paul M Tulkens},
  journal={Trends in pharmacological sciences},
  year={2008},
  volume={29 3},
  pages={
          124-34
        }
}
Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-intermediate S. aureus (VISA) are spreading worldwide, making the search for antibiotics directed against new targets a high priority. Drugs that anchor in the bacterial membrane (e.g. ceragenins and lipopeptides) or that target the bacterial membrane and proteic (lipoglycopeptides) or lipidic (glycodepsipeptides) cell wall precursors seem to have the most potential because they show a fast and extensive bactericidal effect and… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 62 REFERENCES

Antimicrobial activities of ceragenins against clinical isolates of resistant Staphylococcus aureus

  • Chin, J.N
  • Antimicrob. Agents Chemother
  • 2007

Effect of polysorbate-80 on oritavancin binding to plastic surfaces – implications for susceptibility testing

  • Ahrin, F.F
  • In Programme and Abstracts of the 17th European…
  • 2007

In vitro activity profile of oritavancin against resistant staphylococcal populations from a recent surveillance initiative

  • Sahm, D.F
  • In Programme and Abstracts of the 47th…
  • 2007

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