The bacterial adaptive response gene, barA, encodes a novel conserved histidine kinase regulatory switch for adaptation and modulation of metabolism in Escherichia coli

@article{Sahu2003TheBA,
  title={The bacterial adaptive response gene, barA, encodes a novel conserved histidine kinase regulatory switch for adaptation and modulation of metabolism in Escherichia coli},
  author={Surasri Nandan Sahu and Sharmistha Acharya and Helina Tuminaro and Isha R. Patel and Kim Dudley and Joseph E Leclerc and Thomas A. Cebula and Suman Mukhopadhyay},
  journal={Molecular and Cellular Biochemistry},
  year={2003},
  volume={253},
  pages={167-177}
}
Histidine kinases are important prokaryotic determinants of cellular adaptation to environmental conditions, particularly stress. The highly conserved histidine kinase, BarA, encoded by the bacterial adaptive response gene, barA, is a member of the family of tripartite histidine kinases, and is involved in stress adaptation. BarA has been implicated to play a role during infection of epithelial cells. Homologues and orthologues of BarA have been found in pathogenic yeast, fungi, mould and in… CONTINUE READING