The background to Eduard Buchner's discovery of cell-free fermentation

@article{Kohler1971TheBT,
  title={The background to Eduard Buchner's discovery of cell-free fermentation},
  author={Robert E. Kohler,},
  journal={Journal of the History of Biology},
  year={1971},
  volume={4},
  pages={35-61}
}
  • R. Kohler,
  • Published 1971
  • Biology
  • Journal of the History of Biology
Eduard Buchner's discovery of cell-free fermentation in 1897 has long been celebrated as the resolution of one of the most famous scientific controversies of the nineteenth century, the controversy between Pasteur and Liebig over the nature of alcoholic fermentation. Was fermentation, as Pasteur contended, a vital physiological act of the living yeast cell, or was it due as Liebig claimed, to some purely chemical agent within the yeast cell? Could fermentation be separated from intact living… 
The reception of Eduard Buchner's discovery of cell-free fermentation
  • R. Kohler,
  • Biology
    Journal of the history of biology
  • 1972
TLDR
It is claimed that initially, at least, zymase was less a determinant of opinion than a touchstone of pre-existing opinion that revealed the spectrum of existing attitudes toward vital phenomena.
Remembering Our Forebears: Albert Jan Kluyver and the Unity of Life
TLDR
This essay argues that in contrast the careful characterization of fundamental microbial metabolism and physiology by Kluyver made many of the advances of the latter part of the twentieth century possible, by offering a framework which in many respects anticipated the current view of phylogeny.
Activated intermediates: the unexpected may sometimes carry a message.
  • F. Lipmann
  • Chemistry
    BioEssays : news and reviews in molecular, cellular and developmental biology
  • 1985
TLDR
This Roots essay reviews the ways in which a number of activated metabolic intermediates were discovered, and where Fritz Lipmann himself played a leading role, as well as the remarkable earlier discovery of how to prepare a yeast extract that fermented carbohydrate to ethanol.
A history of research on yeasts 3: Emil Fischer, Eduard Buchner and their contemporaries, 1880–1900
Through the discovery of Buchner, Biology was relieved of another fragment of mysticism. The splitting up of sugar into CO2 and alcohol is no more the effect of a "vital principle" than the splitting
Reductionism in the study of enzyme adaptation.
  • P. A. Fields
  • Biology
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
  • 2021
Cell-Free In Vitro Protein Synthesis of Polyketide Synthase Proteins for Production of Natural Products
TLDR
This work suggests that while the CFPS system can generate full length PKS proteins that are sufficiently folded to be recognized, and post-translationally modified by SFP, one or more of the required catalytic domains on these large multidomain proteins is in an inactive state, preventing production of the final product.
The effect of pyruvate accumulation on whole yeast cell transamination
TLDR
Two approaches were followed to decrease the PDC activity: deleting the major structural encoding genes, PDC1 and PDC5, or deleting THI2 which encodes the enzyme responsible for the synthesis of PDC’s co-factor thiamine.
Pus, Sewage, Beer and Milk: Microbiology in Britain, 1870–1940
  • K. Vernon
  • Economics
    History of science; an annual review of literature, research and teaching
  • 1990
TLDR
Although the work of Pasteur and Koch introduced outstandingly important theoretical concepts and methodological innovations, microbiology as a discipline, with journals, societies, full-time posts, etc., did not exist in Britain until the late 1940s, over sixty years after the supposedly seminal discoveries.
Catalytic activity of yeast extract in biofuel cell.
State-of-the-Art Biocatalysis
TLDR
The technological advances that have led to the field’s current state are outlined and it is anticipated that biocatalysis is poised to enable the synthesis of increasingly complex molecules at new levels of efficiency and throughput.
...
...