The bZip proteins CES-2 and ATF-2 alter the timing of transcription for a cell-specific target gene in C. elegans.

@article{Wang2006TheBP,
  title={The bZip proteins CES-2 and ATF-2 alter the timing of transcription for a cell-specific target gene in C. elegans.},
  author={Xiaodong Wang and Hongtao Jia and Helen M. Chamberlin},
  journal={Developmental biology},
  year={2006},
  volume={289 2},
  pages={456-65}
}
The Caenorhabditis elegans basic leucine zipper (bZip) protein CES-2 regulates the transcription of different genes in different cells. Here, we show that CES-2 mediates its effects in one cell (the excretory duct cell) together with another bZip protein, ATF-2. Both proteins influence transactivation of a target gene, lin-48. Although lin-48 is required for both anatomical and physiological features of the excretory duct cell, ces-2 and atf-2 mutants only exhibit anatomical defects. We show… CONTINUE READING
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