The bHLH Repressor Deadpan Regulates the Self-renewal and Specification of Drosophila Larval Neural Stem Cells Independently of Notch

Abstract

Neural stem cells (NSCs) are able to self-renew while giving rise to neurons and glia that comprise a functional nervous system. However, how NSC self-renewal is maintained is not well understood. Using the Drosophila larval NSCs called neuroblasts (NBs) as a model, we demonstrate that the Hairy and Enhancer-of-Split (Hes) family protein Deadpan (Dpn) plays… (More)
DOI: 10.1371/journal.pone.0046724

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@inproceedings{Zhu2012TheBR, title={The bHLH Repressor Deadpan Regulates the Self-renewal and Specification of Drosophila Larval Neural Stem Cells Independently of Notch}, author={Sijun Zhu and Jill Wildonger and Suzanne Barshow and Susan H. Younger and Yaling Huang and Tzumin Lee}, booktitle={PloS one}, year={2012} }