The avian eggshell extracellular matrix as a model for biomineralization.

  title={The avian eggshell extracellular matrix as a model for biomineralization.},
  author={David A. Carrino and James E Dennis and Tsien Ming Wu and Jos{\'e} Luis Arias and Mariela Soledad Fern{\'a}ndez and Javier Rodr{\'i}guez and David J. Fink and Arthur Heuer and Arnold I Caplan},
  journal={Connective tissue research},
  volume={35 1-4},
The avian eggshell is a complex, extracellularly assembled structure which contains both mineralized and non-mineralized regions. The composition of the hen eggshell organic matrix was examined by immunohistochemistry with antibodies to different extracellular matrix molecules. Type I collagen is found in the shell membranes, but only after treatment of the tissue sections with pepsin. When incomplete eggshells are removed from the oviduct and immunostained, type I collagen can be detected in… CONTINUE READING


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