The autophagosome: origins unknown, biogenesis complex

Abstract

Healthy cells use autophagy as a general 'housekeeping' mechanism and to survive stress, including stress induced by nutrient deprivation. Autophagy is initiated at the isolation membrane (originally termed the phagophore), and the coordinated action of ATG (autophagy-related) proteins results in the expansion of this membrane to form the autophagosome… (More)
DOI: 10.1038/nrm3696

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Cite this paper

@article{Lamb2013TheAO, title={The autophagosome: origins unknown, biogenesis complex}, author={Christopher Andrew Lamb and Tamotsu Yoshimori and Sharon A Tooze}, journal={Nature Reviews Molecular Cell Biology}, year={2013}, volume={14}, pages={759-774} }