The autism candidate gene Neurobeachin encodes a scaffolding protein implicated in membrane trafficking and signaling.

@article{Volders2011TheAC,
  title={The autism candidate gene Neurobeachin encodes a scaffolding protein implicated in membrane trafficking and signaling.},
  author={Karolien Volders and Kim Nuytens and John W M Creemers},
  journal={Current molecular medicine},
  year={2011},
  volume={11 3},
  pages={204-17}
}
Autism is a developmental disorder of the central nervous system characterized by impairments in social interaction, communication and restricted repetitive and stereotyped behavior. It is generally assumed that in most cases autism has a polygenic cause, but the pathogenesis is still unknown. Neurobeachin (NBEA) has recently been identified as a candidate gene for autism in a patient with a de novo chromosomal translocation and three patients with a monoallelic deletion. This multidomain… CONTINUE READING