The attenuation of a specific cue-to-consequence association by antiemetic agents

@article{Coil1978TheAO,
  title={The attenuation of a specific cue-to-consequence association by antiemetic agents},
  author={Janet D. Coil and Walter G. Hankins and Donald J. Jenden and J Martinez Garcia},
  journal={Psychopharmacology},
  year={1978},
  volume={56},
  pages={21-25}
}
Previous research has shown that rats develop a conditioned taste aversion after a single pairing of a distinct taste and subsequent toxicosis. The experiments reported here test the hypothesis that the expression of a taste aversion may reflect classically conditioned nausea mediated by activation of brainstem emetic centers by taste stimuli. Rats were allowed to drink a saccharin solution (1 g/l) and 10 min later were intubated with LiCl (180 mg/kg) to produce nausea. When control rats were… CONTINUE READING