The attenuating effects of plumbagin on pro-inflammatory cytokine expression in LPS-activated BV-2 microglial cells.

@article{Messeha2017TheAE,
  title={The attenuating effects of plumbagin on pro-inflammatory cytokine expression in LPS-activated BV-2 microglial cells.},
  author={Samia S. Messeha and Najla O. Zarmouh and Patricia Graziely Antunes de Mendonça and Malak G Kolta and K F A Soliman},
  journal={Journal of neuroimmunology},
  year={2017},
  volume={313},
  pages={129-137}
}
Activated microglial cells produce the pro-inflammatory mediators such as nitric oxide (NO) and cytokines. The excessive release of these mediators can lead to neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). Inhibition of the release of these pro-inflammatory molecules may prevent or halt the progression of these… CONTINUE READING