The atrial natriuretic peptide regulates the production of inflammatory mediators in macrophages.

@article{Kiemer2001TheAN,
  title={The atrial natriuretic peptide regulates the production of inflammatory mediators in macrophages.},
  author={Alexandra K Kiemer and Angelika M. Vollmar},
  journal={Annals of the rheumatic diseases},
  year={2001},
  volume={60 Suppl 3},
  pages={iii68-70}
}
The atrial natriuretic peptide (ANP), a member of the natriuretic peptide family, is a cardiovascular hormone which possesses well defined natriuretic, diuretic, and vasodilating properties. Most of the biological effects of ANP aremediated through its guanylyl cyclase coupled A receptor. Because ANP and its receptors have been shown to be expressed and differentially regulated in the immune system, it has been suggested that ANP has an immunomodulatory potency. Much investigation of the… CONTINUE READING