The athlete biological passport.
@article{Sottas2011TheAB, title={The athlete biological passport.}, author={Pierre-Edouard Sottas and Neil Robinson and Olivier Rabin and Martial Saugy}, journal={Clinical chemistry}, year={2011}, volume={57 7}, pages={ 969-76 } }
BACKGROUND
In elite sports, the growing availability of doping substances identical to those naturally produced by the human body seriously limits the ability of drug-testing regimes to ensure fairness and protection of health.
CONTENT
The Athlete Biological Passport (ABP), the new paradigm in testing based on the personalized monitoring of biomarkers of doping, offers the enormous advantage of being independent of this endless pharmaceutical race. Doping triggers physiological changes that…
187 Citations
The Athlete Biological Passport: How to Personalize Anti-Doping Testing across an Athlete's Career?
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- 2017
The athlete biological passport (ABP) is a new paradigm, complementary to traditional drug testing, based on the personalized monitoring of doping biomarkers, and shares multiple aspects with the present customization of health care and personalized medicine.
Current implementation and future of the Athlete Biological Passport.
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The ability of the Athlete Biological Passport to detect doping is limited if the physiological result of a low level of doping remains within the individual's own reference range.
A performance passport in cycling: facts and fancy
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St stratagems adopted by athletes to circumvent being flagged in the Athlete Biological Passport will be described, the effect of confounding factors on biological and performance variables will be highlighted, and a pragmatic strategy to strengthen the ABP through aphysiological module including performance factors will be presented.
Future opportunities for the Athlete Biological Passport
- BiologyFrontiers in Sports and Active Living
- 2022
This perspective article highlights the current innovations of the Athlete Biological Passport that seem the most promising and provides an opportunity to bring together approaches that are more widely exploited and others in the early stages of investigation seeking to develop the ABP.
Monitoring of biological markers indicative of doping: the athlete biological passport
- MedicineBritish Journal of Sports Medicine
- 2014
The athlete biological passport (ABP) was recently implemented in anti-doping work and is based on the individual and longitudinal monitoring of haematological or urine markers. These may be…
The athlete biological passport: challenges and possibilities
- MedicineInternational Journal of Sport Policy and Politics
- 2019
The Athlete Biological Passport relies on the longitudinal monitoring of blood and urine variables impacted by doping use and the inclusion of additional data in the ABP, such as variables involved in hormonal axes or -omics data, could bring new challenges.
Athlete Biological Passport: Practical Application in Sports
- EducationJournal of Postgraduate Medicine, Education and Research
- 2020
bstrAct The role of athlete biological passport (ABP) is the longitudinal tracking of the doping biomarkers. There are three modules of this program: hematological, steroidal, and endocrinological.…
Fighting Doping in Elite Sports: Blood for All Tests!
- BiologyFront. Sports Act. Living
- 2019
The opportunities of blood samples to monitor not only hematological but also steroid profiles in elite athletes are explored and steroid hormones quantification in blood showed a promising ability to detect testosterone doping.
Ten years of collecting hematological athlete biological passport samples—perspectives from a National Anti-doping Organization
- EducationFrontiers in sports and active living
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The hematological module of the Athlete Biological Passport (ABP) aims to reveal blood doping indirectly by looking at selected biomarkers of doping over time. For Anti-Doping Organizations (ADOs),…
Athlete Biological Passport: Need and Challenges
- BiologyIndian Journal of Orthopaedics
- 2020
The Athlete Biological Passport programme was initiated in 2009 by the World Anti-Doping Agency for making the anti-doping programme more effective and stronger and reflects the changes in biological markers collated over an athlete’s career.
References
SHOWING 1-10 OF 34 REFERENCES
Endogenous steroid profiling in the athlete biological passport.
- BiologyEndocrinology and metabolism clinics of North America
- 2010
The athlete's biological passport and indirect markers of blood doping.
- Computer ScienceHandbook of experimental pharmacology
- 2010
Forensic techniques for the evaluation of the evidence, and more particularly Bayesian networks, allow antidoping authorities to take into account firstly the natural variations of indirect markers - through a mathematical formalism based on probabilities - and secondly the complexity due to the multiplicity of causes and confounding effects through a distributed and flexible graphical representation.
Hematologic passport for athletes competing in endurance sports: a feasibility study.
- MedicineHaematologica
- 2003
The hematologic passport is feasible and might be employed to exclude athletes with non-physiologic increases in hemoglobin and hematocrit from competitions and should be used within a global strategy to deter blood doping.
Performance profiling: a role for sport science in the fight against doping?
- BiologyInternational journal of sports physiology and performance
- 2009
A new strategy to improve the targeting of suspicious athletes might be the longitudinal monitoring of individual performances, which might improve the effectiveness in the fight against doping considerably.
A strategy to deter blood doping in sport.
- MedicineHaematologica
- 2002
This article will apply logic to known doping strategies, with an emphasis on the abuse of recombinant human erythropoietin that reflects the prevalence of its abuse in the sporting community.
Statistical Classification of Abnormal Blood Profiles in Athletes
- Medicine
- 2006
A new indirect and universal test of blood doping, called Abnormal Blood Profile Score (ABPS), is developed, based on the statistical classification of indirect biomarkers of altered erythropoiesis, which is sensitive to any form of blood transfusion, autologous transfusion included.
Second-generation blood tests to detect erythropoietin abuse by athletes.
- MedicineHaematologica
- 2003
The increased stability of the new blood parameters facilitates transport of samples to central laboratories, and the heightened sensitivity of thenew models makes them better than existing models for federations wishing to screen samples for urine testing and to identify and target suspect athletes for out-of-competition testing.
From population- to subject-based limits of T/E ratio to detect testosterone abuse in elite sports.
- BiologyForensic science international
- 2008
Development of reference ranges in elite athletes for markers of altered erythropoiesis.
- MedicineHaematologica
- 2002
Assessment of an athlete's blood parameters and ON- and OFF-model scores may need adjustment for training modalities and other characteristics of the subject.
Mass spectrometry in sports drug testing: Structure characterization and analytical assays.
- ChemistryMass spectrometry reviews
- 2007
The versatility of modern mass spectrometers enable specific as well as comprehensive measurements allowing sports drug testing laboratories to determine the misuse of therapeutics such as anabolic-androgenic steroids, stimulants, masking agents or so-called designer drugs in athletes' blood or urine specimens, and a selection of recent developments is summarized in this review.