The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae.

@article{Hu1999TheAE,
  title={The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae.},
  author={H Hu and Grant N Pierce and Guangming Zhong},
  journal={The Journal of clinical investigation},
  year={1999},
  volume={103 5},
  pages={747-53}
}
Epidemiological investigations have linked Chlamydia pneumoniae infection to atherosclerosis. It is not clear, however, whether C. pneumoniae infection plays a causal role in the development of atherosclerosis. Mice with low-density lipoprotein receptor deficiency were induced to develop atherosclerotic lesions in aorta with a cholesterol-enriched diet that increased serum cholesterol by two- to threefold. Using this mouse model, we found that the chlamydial infection alone with either the C… CONTINUE READING

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