The asymmetry defect of hippocampal circuitry impairs working memory in β2-microglobulin deficient mice.


Left-right (L-R) asymmetry is a fundamental feature of brain function, but the mechanisms underlying functional asymmetry remain largely unknown. We previously identified structural and functional asymmetries in the circuitry of the mouse hippocampus that result from the asymmetrical distribution of NMDA receptor GluR ε2 (NR2B) subunits. By examining the… (More)
DOI: 10.1016/j.nlm.2016.12.020

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