The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis.

@article{Nijveldt2003TheAD,
  title={The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis.},
  author={Robert J. Nijveldt and Tom Teerlink and Paul A. M. van Leeuwen},
  journal={Clinical nutrition},
  year={2003},
  volume={22 1},
  pages={
          99-104
        }
}
Development of multiple organ failure is the most complex problem in critically ill patients, and is associated with a high mortality. Asymmetrical dimethylarginine (ADMA) is an endogenously produced inhibitor of nitric oxide synthase, of which the clinical importance is currently being revealed. In Nijveldt et al. (The liver is an important organ in the metabolism of asymmetrical dimethylargenine (ADMA) Clin Nutr 2003; 22: 17-22) we showed that plasma ADMA concentration is elevated in… CONTINUE READING
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