The astrocyte in multiple sclerosis revisited

@article{Brosnan2013TheAI,
  title={The astrocyte in multiple sclerosis revisited},
  author={Celia F. Brosnan and Cedric S. Raine},
  journal={Glia},
  year={2013},
  volume={61}
}
Among the constituent cell types of the multiple sclerosis (MS) plaque, the astrocyte has been the least considered as a player in the pathogenesis of the lesion. Traditionally, it has been assigned a secondary scarring role with little or no role in lesion formation or repair. However, the recent upsurge of interest in the demyelinating condition neuromyelitis optica (NMO) has resulted in NMO being identified as the first disease of myelin in which primary damage to astrocytes, resulting from… 
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