The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study.

@article{Greendale2005TheAO,
  title={The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study.},
  author={Gail A Greendale and Shana L. Palla and Giske A Ursin and Gail A. Laughlin and Carolyn J. Crandall and Malcolm C. Pike and Beth A. Reboussin},
  journal={American journal of epidemiology},
  year={2005},
  volume={162 9},
  pages={826-34}
}
Mammographic density is an independent risk factor for breast cancer. In postmenopausal women, higher levels of endogenous sex steroids are associated with an increased risk of breast cancer. Limited prior data suggest that endogenous sex steroids either are not associated (total estradiol and progesterone) or are negatively associated (free estradiol) with higher mammographic density. To analyze the associations between endogenous sex steroids and mammographic density, the authors conducted a… CONTINUE READING