The association of arrestin-3 with the follitropin receptor depends on receptor activation and phosphorylation.

@article{Krishnamurthy2003TheAO,
  title={The association of arrestin-3 with the follitropin receptor depends on receptor activation and phosphorylation.},
  author={Hanumanthappa Krishnamurthy and Colette Galet and Mario Ascoli},
  journal={Molecular and cellular endocrinology},
  year={2003},
  volume={204 1-2},
  pages={127-40}
}
We have recently shown that the binding of arrestin-3 to the lutropin receptor (LHR) is dependent mostly on receptor activation rather than on phosphorylation. The experiments presented here were designed to test the involvement of these two events in the association of arrestin-3 with the closely related follitropin receptor (FSHR). Activation of the FSHR leads to the phosphorylation of residues in the first and third intracellular loops. Mutation of the phosphorylation sites in the third… CONTINUE READING
Highly Cited
This paper has 26 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…